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Gavin Giovannoni Selected Research

ocrelizumab

10/2022Simulated treatment comparison of efficacy outcomes for ofatumumab in ASCLEPIOS I/II versus ocrelizumab in OPERA I/II for the treatment of patients with relapsing multiple sclerosis.
1/2022Risk of requiring a walking aid after 6.5 years of ocrelizumab treatment in patients with relapsing multiple sclerosis: Data from the OPERA I and OPERA II trials.
1/2022CD19 B cell repopulation after ocrelizumab, alemtuzumab and cladribine: Implications for SARS-CoV-2 vaccinations in multiple sclerosis.
12/2018Ocrelizumab reduces progression of upper extremity impairment in patients with primary progressive multiple sclerosis: Findings from the phase III randomized ORATORIO trial.
1/2018No evidence of disease activity (NEDA) analysis by epochs in patients with relapsing multiple sclerosis treated with ocrelizumab vs interferon beta-1a.
2/2017Memory B Cells are Major Targets for Effective Immunotherapy in Relapsing Multiple Sclerosis.
1/2017Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis.
1/2017Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis.

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Gavin Giovannoni Research Topics

Disease

184Multiple Sclerosis
11/2022 - 10/2002
56Relapsing-Remitting Multiple Sclerosis
06/2022 - 09/2003
16Chronic Progressive Multiple Sclerosis
09/2022 - 09/2003
16Disease Progression
10/2019 - 10/2004
12Infections
11/2021 - 02/2012
10Atrophy
01/2022 - 12/2010
10Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2017 - 05/2005
9COVID-19
08/2022 - 01/2020
9Demyelinating Diseases (Demyelinating Disease)
06/2022 - 04/2003
8Inflammation (Inflammations)
06/2022 - 05/2005
8Lymphopenia (Lymphocytopenia)
07/2021 - 02/2010
6Neurodegenerative Diseases (Neurodegenerative Disease)
06/2022 - 01/2010
6Autoimmune Diseases (Autoimmune Disease)
01/2022 - 04/2007
6Neoplasms (Cancer)
01/2020 - 01/2017
6Movement Disorders (Movement Disorder)
11/2014 - 08/2004
5Progressive Multifocal Leukoencephalopathy
01/2022 - 04/2010
5Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
10/2020 - 03/2014
5Nervous System Diseases (Neurological Disorders)
11/2014 - 11/2006
5Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
05/2012 - 08/2004
5Chorea (Rheumatic Chorea)
04/2009 - 03/2003
4Infectious Mononucleosis (Glandular Fever)
10/2020 - 01/2009
4Neuromyelitis Optica (Devic's Disease)
09/2020 - 01/2011
4Herpes Zoster
04/2019 - 02/2010
4Parkinson Disease (Parkinson's Disease)
01/2018 - 05/2008
4Streptococcal Infections (Streptococcal Infection)
05/2012 - 08/2004
3Epstein-Barr Virus Infections
01/2022 - 06/2007
3Headache (Headaches)
07/2021 - 11/2014
3Chickenpox
01/2019 - 01/2009
3Hypersensitivity (Allergy)
01/2019 - 03/2006
3Neuroinflammatory Diseases
01/2017 - 01/2011
3Optic Neuritis (Retrobulbar Neuritis)
03/2016 - 06/2008
3Encephalitis (Encephalitis, Rasmussen)
08/2010 - 01/2004
2Rheumatoid Arthritis
08/2021 - 07/2012
2Nausea
07/2021 - 09/2012
2Opportunistic Infections (Opportunistic Infection)
04/2019 - 11/2018
2Human Influenza (Influenza)
01/2019 - 01/2004
2Meningitis
01/2019 - 08/2010
2Urinary Tract Infections (Urinary Tract Infection)
01/2019 - 07/2016
2HIV Infections (HIV Infection)
08/2018 - 01/2015
2Vitamin D Deficiency
02/2018 - 07/2013
2Hypertension (High Blood Pressure)
01/2018 - 12/2012
2Spinal Cord Injuries (Spinal Cord Injury)
01/2018 - 03/2015
2Body Weight (Weight, Body)
01/2018 - 02/2010
2Ulcerative Colitis
07/2016 - 07/2012
2Exanthema (Rash)
03/2016 - 06/2013

Drug/Important Bio-Agent (IBA)

31CladribineFDA LinkGeneric
06/2022 - 02/2010
29AntibodiesIBA
11/2021 - 11/2003
26Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2006
22TabletsIBA
06/2022 - 02/2010
18Alemtuzumab (Campath)FDA Link
01/2022 - 03/2012
18Natalizumab (Tysabri)FDA Link
01/2022 - 03/2006
15Dimethyl FumarateIBA
01/2018 - 09/2012
14Fingolimod Hydrochloride (FTY720)FDA Link
08/2022 - 07/2011
13InterferonsIBA
01/2021 - 09/2004
13Interferon beta-1aFDA Link
01/2018 - 10/2004
12Interferon-betaIBA
01/2015 - 09/2003
11Monoclonal AntibodiesIBA
11/2022 - 03/2012
11Vitamin DFDA LinkGeneric
01/2020 - 06/2007
10Pharmaceutical PreparationsIBA
01/2022 - 05/2010
8ocrelizumabIBA
10/2022 - 01/2017
8siponimodIBA
09/2022 - 02/2017
8Proteins (Proteins, Gene)FDA Link
08/2021 - 12/2008
8Daclizumab (Zenapax)FDA Link
10/2020 - 06/2013
8CannabinoidsIBA
08/2017 - 05/2003
7Neutralizing AntibodiesIBA
11/2021 - 06/2007
7GadoliniumIBA
01/2020 - 07/2006
6AntigensIBA
11/2021 - 05/2005
5VaccinesIBA
08/2022 - 06/2020
5HLA-DRB1 Chains (HLA DRB1)IBA
10/2020 - 01/2010
5Immunoglobulin G (IgG)IBA
01/2013 - 01/2003
4Sphingosine-1-Phosphate ReceptorsIBA
09/2022 - 07/2011
4Neuroprotective AgentsIBA
01/2020 - 01/2013
4Glatiramer Acetate (Copaxone)FDA Link
02/2017 - 05/2005
4EnzymesIBA
07/2016 - 03/2006
4daclizumab HYPIBA
05/2014 - 06/2013
3Immunoglobulins (Immunoglobulin)IBA
01/2022 - 10/2019
3Indicators and Reagents (Reagents)IBA
08/2021 - 12/2014
3Oligoclonal BandsIBA
10/2019 - 04/2003
3Rituximab (Mabthera)FDA Link
02/2017 - 03/2016
3AutoantibodiesIBA
05/2015 - 03/2003
3Biological ProductsIBA
09/2014 - 07/2009
3Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
06/2013 - 08/2010
2opicinumabIBA
02/2022 - 01/2019
2Biotin (Vitamin H)FDA Link
02/2022 - 12/2020
2Cytidine Diphosphate (CDP)IBA
01/2022 - 12/2018
2COVID-19 VaccinesIBA
01/2022 - 01/2021
2AutoantigensIBA
11/2021 - 03/2006
2RNA (Ribonucleic Acid)IBA
10/2020 - 01/2004
2Transaminases (Aminotransferases)IBA
01/2018 - 09/2012
2Dopamine (Intropin)FDA LinkGeneric
01/2018 - 07/2009
2Minocycline (Cyclops)FDA LinkGeneric
01/2018 - 03/2015
2Gonadal HormonesIBA
11/2016 - 10/2014
2CytokinesIBA
04/2016 - 01/2013
2Sodium Channels (Sodium Channel)IBA
03/2016 - 01/2014
2Voltage-Gated Sodium ChannelsIBA
03/2016 - 06/2015
2Salivary Proteins and PeptidesIBA
12/2015 - 10/2015

Therapy/Procedure

60Therapeutics
10/2022 - 11/2003
7Immunotherapy
04/2021 - 05/2005
2Injections
11/2021 - 05/2018
2Precision Medicine
11/2021 - 11/2017